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Basic protocol

Basic protocol

540.56 to renew 2 times

The basic protocol is scalable in its dosage. From the fourth week, the doses are maximum and constant until the 68th week.

This pack has sufficient quantities for 24 weeks, to be renewed twice.




Basic protocol (68 weeks)

Weeks 1 2 3 4-68 Total
Polygonum c. (per day in 3 times) 3 6 9 12 7406 capsules
Andrographis p. (per day in 3 times) 3 6 9 12 7406 capsules
Uncaria t. (per day in 3 times) 3 6 9 12 7406 capsules


This pack contains

The quantities provided in this pack correspond to a duration of 24 weeks, to be renewed twice.


Andrographis paniculata / Andrographis

5 boxes of 500 capsules

Andrographis paniculata is the main herb in the Buhner Protocol that has antitreponemal effect. It readily crosses the blood-brain barrier and accumulates in the tissues of the central nervous system – in the brain, spinal cord, cerebrospinal fluid. Because of its broad systemic effect on the body, it both protects the body from damage due to infection and kills the spirochetes where they nested and at the same time provides an overall systemic immune boost. It protects the heart muscle. When using this herb, you must remember that it can cause allergic reactions in the form of rashes (in about 1% of people). You should start with a small dose and gradually increase it while observing the body’s reaction. If such a reaction occurs, the herb should be discontinued.
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Uncaria tomentosa / Cat’s Claw

5 boxes of 500 capsules

Cat’s Claw (Lat. Uncaria tomentosa) is the primary herb in the Buhner protocol recommended for immune system regulation. This herb modulates the action of the immune system, increasing its strength when necessary and, if necessary, lowering excessive reactions. One of the most beneficial aspects of treating Lyme disease with Cat’s Claw is that it contributes to the growth of CD57+ cells which play an important role in the proper functioning of the immune system. When Lyme spirochetes are present in the body, they specifically inhibit the production of this subset of immune system cells. A low CD57 titer is a reliable marker in chronic Lyme disease, especially when antibiotic therapy has no effect. This ability to increase the CD57 cell count in Lyme disease patients is one of the reasons for the good results in the treatment of chronic or late Lyme disease. The use of Cat’s Claw helps to maintain high levels of CD57, which in turn helps to inhibit the progression of the disease. In addition, it has a specific anti-inflammatory effect in the treatment of joint and muscle pain in Lyme disease, reduces swelling and also has a positive effect on the nervous system. Cat’s claw must not be taken by people taking blood thinners. People who are scheduled for surgery must stop taking the herb 10 days before any planned surgery. Cat’s Claw should not be taken during treatment with drugs that inhibit gastric acid secretion because these can also inhibit the conversion of the herb to its active form in the stomach.
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Reynoutria japonica / Japanese Knotweed

5 boxes of 500 capsules

Japanese knotweed (Lat. Polygonum cuspidatum) is the primary herb included in the Buhner Protocol. Its role in the treatment of Lyme disease is significant. Japanese knotweed is a herb that exhibits antimicrobial activity, including activity against Lyme spirochetes as well as antiviral activity. It protects the integrity of the vascular endothelium which prevents the penetration of Borrelia bacteria and other co-infections, thus protecting against damage caused by them. It stimulates microcirculation, especially in the joints, heart, eyeballs, brain and skin and is therefore important in transporting active ingredients to areas affected by pathogenic microorganisms. The active ingredients of Japanese knotweed pass through the blood-brain barrier and affect the central nervous system where they have anti-spirochete and anti-inflammatory effects. Japanese Knotweed contributes to the reduction of inflammation in tissues and therefore reduces the impact of Borrelia bacteria in both joints and skin. It protects and improves heart function and reduces inflammation in tissues and is helpful for cardiac symptoms in Lyme disease such as palpitations, chest pain, shortness of breath and dizziness. Importantly, it lowers the body’s autoimmune response to Lyme disease. It helps to lower the strength of the Herxheimer reaction. This herb also reduces the production of reactive oxygen species in the brain and central nervous system. Japanese knotweed should not be used together with blood thinners. The use of this herb should be discontinued ten days before a planned surgical procedure.
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Usage precautions


  • Andrographis paniculata: can cause allergic reactions in the form of skin rashes (in about 1% of people). Not to be used during pregnancy. Inhibits progesterone production, should not to be used by women when trying to conceive. May cause mild constipation. Should not be used in active gall bladder disease.
  • Uncaria tomentosa: because of the immune-stimulating actions, do not use if you have had an organ transplant or are using immunosuppressive drugs. Do not use if you are using blood-thinning medications or are scheduled for surgery. Do not use if you are trying to become pregnant or are pregnant. Caution should be exercised if you have low blood pressure.
  • Polygonum cuspidatum: bothersome side effect that seems to occur in about 1 percent of the people using the herb is loss of taste. Side effects and quite rare are primarily gastrointestinal in nature : dry mouth, bitter taste in mouth, nausea, vomiting, abdominal pain, and diarrhea (rare). Contraindicated in pregnancy.

In addition to the protocol

Although the basic protocol is sufficient on its own, it is strongly recommended to add the collagen support to it in order to reconstitute it. We also suggest the addition of Burbur to prevent any possible Herx reaction.


Collagen support




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